The use of the mechanical fragility test in evaluating sublethal RBC injury during storage.

@article{Raval2010TheUO,
  title={The use of the mechanical fragility test in evaluating sublethal RBC injury during storage.},
  author={Jay S Raval and Jonathan H Waters and A Seltsam and Erwin A Scharberg and Ekkehard Richter and Amanda R Daly and Marina V. Kameneva and M H Yazer},
  journal={Vox sanguinis},
  year={2010},
  volume={99 4},
  pages={325-31}
}
BACKGROUND The mechanical fragility index (MFI) is an in vitro measurement of the extent of RBC sublethal injury. Sublethal injury might constitute a component of the RBC storage lesion, thus the MFI was determined serially during routine RBC storage. METHODS Leucoreduced AS-5- and SAGM-preserved RBCs were stored under routine blood bank conditions. The mechanical fragility (MF) of each unit was serially measured during storage. RESULTS For both AS-5 and SAGM units, male and female RBCs… CONTINUE READING