The use of the BD oxygen biosensor system to assess isolated human islets of langerhans: oxygen consumption as a potential measure of islet potency.

@article{Fraker2006TheUO,
  title={The use of the BD oxygen biosensor system to assess isolated human islets of langerhans: oxygen consumption as a potential measure of islet potency.},
  author={Chris A Fraker and M. Timmins and Richard D. Guarino and Perry D. Haaland and Hirohito Ichii and Damaris Molano and Antonello Pileggi and Raffaella Poggioli and Sharon C. Presnell and Luca Alessandro Inverardi and Mitra Zehtab and Camillo Ricordi},
  journal={Cell transplantation},
  year={2006},
  volume={15 8-9},
  pages={745-58}
}
The measurement of cellular oxygen consumption rate (OCR) is a potential tool for the assessment of metabolic potency of isolated islets of Langerhans prior to clinical transplantation. We used a commercially available 96-well plate fluoroprobe, the BD Oxygen Biosensor System (OBS), to estimate OCR in 27 human islet preparations, and compared these results to those of concurrent mouse transplantations. OCR was estimated both from the dO2 at steady state and from the transient rate of change of… CONTINUE READING

From This Paper

Topics from this paper.
22 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 22 extracted citations

Similar Papers

Loading similar papers…