• DOI:10.1586/ern.12.42
Corpus ID: 43706704

The use of sodium oxybate to treat narcolepsy

@article{Mayer2012TheUO,
  title={The use of sodium oxybate to treat narcolepsy},
  author={G. Mayer},
  journal={Expert Review of Neurotherapeutics},
  year={2012},
  volume={12},
  pages={519 - 529}
}

G. Mayer

Published 2012

Medicine

Expert Review of Neurotherapeutics

Narcolepsy is a life-long neurodegenerative disorder that causes considerable impairment to quality of life. Until the 1970s, the treatment for one of the main symptoms, excessive daytime sleepiness, was restricted to stimulants, whereas the second core symptom, cataplexy, was treated with antidepressants, and the resultant fragmented night-time sleep with hypnotics. Sodium oxybate (Xyrem®, UCB Pharma, Brussels, Belgium) is an efficacious drug for all three symptoms which improves the quality… CONTINUE READING

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