The use of small fraction numbers in high dose-rate gynaecological afterloading: some radiobiological considerations.

@article{Dale1990TheUO,
  title={The use of small fraction numbers in high dose-rate gynaecological afterloading: some radiobiological considerations.},
  author={Roger G. Dale},
  journal={The British journal of radiology},
  year={1990},
  volume={63 748},
  pages={290-4}
}
Using commonly assumed alpha/beta ratios for tumours and late-reacting tissues, the linear-quadratic (LQ) model has been used to compare low dose-rate (LDR) gynaecological treatment with high dose-rate (HDR) techniques given in small fraction numbers. Even in the absence of relatively favourable tissue recovery constants (mu values) it is shown that, provided a modest extra amount of geometrical sparing of critical tissues is available (by means of spacing or shielding), HDR treatment in a… CONTINUE READING

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