The use of radioimmunoassay to compare the tissue and subcellular distributions of neurotensin and neuromedin N in the cat.
@article{Carraway1987TheUO, title={The use of radioimmunoassay to compare the tissue and subcellular distributions of neurotensin and neuromedin N in the cat.}, author={R. Carraway and S. P. Mitra}, journal={Endocrinology}, year={1987}, volume={120 5}, pages={ 2092-100 } }
A RIA for neuromedin N (NMN) was developed using 125I-labeled NMN and rabbit antisera raised against a synthetic NMN coupled to NH2-enriched putrescine-thyroglobulin. One of the antisera (TG-B), which cross-reacted less than 3% with the related substances, neurotensin (NT), Lys8,Asn9-NT8-13, and xenopsin, was used to compare the distribution of immunoreactive NMN (iNMN) in the cat to that of immunoreactive NT (iNT). Although both iNMN and iNT were found primarily in the mucosa of the ileum… CONTINUE READING
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References
SHOWING 1-10 OF 23 REFERENCES
Radioimmunoassay for Lys8, Asn9, neurotensin 8–13: Tissue and subcellular distribution of immunoreactivity in chickens
- Biology, Medicine
- Peptides
- 1983
- 34
Radioimmunoassay for neurotensin, a hypothalamic peptide.
- Chemistry, Medicine
- The Journal of biological chemistry
- 1976
- 197
- PDF
Characterization of radioimmunoassayable neurotensin in the rat. Its differential distribution in the central nervous system, small intestine, and stomach.
- Biology, Medicine
- The Journal of biological chemistry
- 1976
- 488
Immunochemical characterization of neurotensin-like peptides in chicken
- Biology, Medicine
- Peptides
- 1980
- 56
Potential precursors to neuromedin N in the cat and their processing by pepsin.
- Biology, Medicine
- Endocrinology
- 1987
- 12
Isolation, biological and chemical characterization, and synthesis of a neurotensin-related hexapeptide from chicken intestine.
- Medicine, Chemistry
- The Journal of biological chemistry
- 1983
- 79
The comparative distribution of [Lys8-Asn9]-neurotensin8–13-like immunoreactivity in chicken and rat tissues
- Chemistry, Medicine
- Brain Research
- 1985
- 5
Isolation, structure and biologic activity of chicken intestinal neurotensin
- Biology, Medicine
- Peptides
- 1980
- 81
Neurotensin. Immunohistochemical localization in central and peripheral nervous system and in endocrine cells and its functional role as neurotransmitter and endocrine hormone.
- Biology, Medicine
- Progress in histochemistry and cytochemistry
- 1985
- 167