The use of propensity scores in pharmacoepidemiologic research.

  title={The use of propensity scores in pharmacoepidemiologic research.},
  author={Susan M. Perkins and Wanzhu Tu and M G Underhill and Xiao-Hua Zhou and Michael D. Murray},
  journal={Pharmacoepidemiology and drug safety},
  volume={9 2},
PURPOSE To describe the application of propensity score analysis in pharmacoepidemiologic research using a study comparing the renal effects of two commonly prescribed non-steroidal anti-inflammatory drugs (NSAIDs). METHOD Observational data were collected on the change in renal function, as measured by serum creatinine concentration, before and after use of two NSAIDs, Ibuprofen and Sulindac. To estimate the treatment effect of the different NSAIDs, we used the propensity score methodology… CONTINUE READING

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