The use of polygenic risk scores to identify phenotypes associated with genetic risk of schizophrenia: Systematic review

@article{Mistry2018TheUO,
  title={The use of polygenic risk scores to identify phenotypes associated with genetic risk of schizophrenia: Systematic review},
  author={S. Mistry and Judith R Harrison and D. Smith and V. Escott-Price and S. Zammit},
  journal={Schizophrenia Research},
  year={2018},
  volume={197},
  pages={2-8}
}
Studying the phenotypic manifestations of increased genetic liability for schizophrenia can increase our understanding of this disorder. Specifically, information from alleles identified in genome-wide association studies can be collapsed into a polygenic risk score (PRS) to explore how genetic risk is manifest within different samples. In this systematic review, we provide a comprehensive assessment of studies examining associations between schizophrenia PRS (SZ-PRS) and several phenotypic… Expand
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