The use of novel lymphatic endothelial cell-specific immunohistochemical markers to differentiate cutaneous angiosarcomas in dogs.

@article{Halsey2016TheUO,
  title={The use of novel lymphatic endothelial cell-specific immunohistochemical markers to differentiate cutaneous angiosarcomas in dogs.},
  author={Charles H C Halsey and Deanna Rae Worley and Kaitlin M Curran and Joseph B Charles and E. J. Ehrhart},
  journal={Veterinary and comparative oncology},
  year={2016},
  volume={14 3},
  pages={236-44}
}
Lymphangiosarcomas are uncommon vascular neoplasms that arise from lymphatic endothelial cells (LECs). They efface and replace normal subcutaneous tissue and are characterised by arborising, vascular channels lined by a single layer of pleomorphic endothelial cells and a paucity of erythrocytes. Lymphangiosarcomas are architecturally similar to hemangiosarcomas, a common malignancy of vascular origin arising from blood vascular endothelial cells. Common immunohistochemical markers for vascular… CONTINUE READING
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