The use of mushroom-forming fungi for the production of N-glycosylated therapeutic proteins.

@article{Berends2009TheUO,
  title={The use of mushroom-forming fungi for the production of N-glycosylated therapeutic proteins.},
  author={Elsa Berends and Karin Scholtmeijer and Han A. B. W{\"o}sten and D. Bosch and Luis G. Lugones},
  journal={Trends in microbiology},
  year={2009},
  volume={17 10},
  pages={439-43}
}
The market for N-glycosylated therapeutic proteins represents multi-billion dollars in sales and is growing more than 10% each year. This requires cost-effective production platforms that display correct and homogeneous N-glycosylation. Based on recent results, we propose to use mushroom-forming basidiomycetes for the production of N-glycosylated therapeutic proteins. 

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