The use of metformin in the management of polycystic ovary syndrome and associated anovulatory infertility: The current evidence

@article{Leeman2009TheUO,
  title={The use of metformin in the management of polycystic ovary syndrome and associated anovulatory infertility: The current evidence},
  author={Lawrence Leeman and Umesh Acharya},
  journal={Journal of Obstetrics and Gynaecology},
  year={2009},
  volume={29},
  pages={467 - 472}
}
  • L. Leeman, U. Acharya
  • Published 1 January 2009
  • Medicine, Biology
  • Journal of Obstetrics and Gynaecology
Summary Women suffering from anovulatory infertility are frequently diagnosed with polycystic ovary syndrome (PCOS), which is a varied condition of ovarian dysfunction characterised by hyperandrogenaemia and abnormal ovarian morphology. PCOS has been associated with insulin resistance, leading to the insulin-sensitising agent, metformin, being investigated as a useful therapy for the reinstatement of normal ovarian function and regular ovulation. While some trials and meta-analyses have… 

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