The use of lentiviral vectors to obtain transgenic rats.

  title={The use of lentiviral vectors to obtain transgenic rats.},
  author={S{\'e}verine R{\'e}my and Tuan Huy Nguyen and S{\'e}verine M{\'e}noret and Laurent Tesson and Claire Usal and Ignacio Anegon},
  journal={Methods in molecular biology},
Lentiviral vectors are now well recognized as good vehicles for gene delivery. This is because they can efficiently transduce both dividing and post-mitotic cells, and stably integrate into the host genome allowing for long-term expression of the transgene. Their potential utility for the generation of transgenic animals has been recognized as an attractive and promising alternative to the conventional DNA-microinjection method which lacks efficiency. The initial success of lentiviral… CONTINUE READING

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