The use of laboratory tests in diagnosis and monitoring of systemic lupus erythematosus.

@article{Sinico2002TheUO,
  title={The use of laboratory tests in diagnosis and monitoring of systemic lupus erythematosus.},
  author={Renato A Sinico and Bruna Bollini and Ettore Sabadini and Luca Di Toma and Antonella Radice},
  journal={Journal of nephrology},
  year={2002},
  volume={15 Suppl 6},
  pages={S20-7}
}
Clinical immunology laboratories play an essential role in diagnosis and monitoring of systemic lupus erythematosus (SLE). To obtain the best results in terms of diagnostic performance and clinical usefulness, the following recommendations should be fulfilled: Indirect immunofluorescence on Hep-2 cells remains the method of choice for the detection of anti-nuclear antibodies (ANA). The sensitivity of ANA test for SLE is very high (almost 100%) but its specificity low since ANA can be present in… CONTINUE READING

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