The use of hsa-miR-21, hsa-miR-181b and hsa-miR-106a as prognostic indicators of astrocytoma.

@article{Zhi2010TheUO,
  title={The use of hsa-miR-21, hsa-miR-181b and hsa-miR-106a as prognostic indicators of astrocytoma.},
  author={Feng Zhi and Xiao Dong Chen and Suinuan Wang and Xiwei Xia and Yimin Shi and Wenxue Guan and Naiyuan Shao and Hongtao Qu and Changchun Yang and Yi Zhang and Qiang Wang and Rong Wang and Ke Zen and Chen-yu Zhang and Junfeng Zhang and Yilin Yang},
  journal={European journal of cancer},
  year={2010},
  volume={46 9},
  pages={
          1640-9
        }
}
BACKGROUND The aberrant expression of microRNAs (miRNAs) is associated with a variety of diseases including cancers. In the present study, the miRNA expression profile was examined in astrocytoma, a malignant and prevalent intracranial tumour in adults. METHODS We screened the expression profile of 200 miRNAs in a training sample set consisting of 84 astrocytoma samples and 20 normal adjacent tissue (NAT) samples using the method of stem-loop quantitative RT-PCR. The significantly altered… CONTINUE READING

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