The use of gold nanoparticle aggregation for DNA computing and logic-based biomolecular detection.

Abstract

The use of DNA molecules as a physical computational material has attracted much interest, especially in the area of DNA computing. DNAs are also useful for logical control and analysis of biological systems if efficient visualization methods are available. Here we present a quick and simple visualization technique that displays the results of the DNA computing process based on a colorimetric change induced by gold nanoparticle aggregation, and we apply it to the logic-based detection of biomolecules. Our results demonstrate its effectiveness in both DNA-based logical computation and logic-based biomolecular detection.

DOI: 10.1088/0957-4484/19/39/395103

Extracted Key Phrases

4 Figures and Tables

Cite this paper

@article{Lee2008TheUO, title={The use of gold nanoparticle aggregation for DNA computing and logic-based biomolecular detection.}, author={In-Hee Lee and Kyung-Ae Yang and Ji-Hoon Lee and Ji-Yoon Park and Young Gyu Chai and Jae-Hoon Lee and Byoung-Tak Zhang}, journal={Nanotechnology}, year={2008}, volume={19 39}, pages={395103} }