The use of cytochemical procedures in the diagnosis and management of acute and chronic myeloid leukemia.

@article{Elghetany1990TheUO,
  title={The use of cytochemical procedures in the diagnosis and management of acute and chronic myeloid leukemia.},
  author={Mohamed Tarek Elghetany and J M Maccallum and Frederick R. Davey},
  journal={Clinics in laboratory medicine},
  year={1990},
  volume={10 4},
  pages={
          707-20
        }
}
The use of Wright-Giemsa-stained smears alone for the classification of acute leukemias often proves unsatisfactory. Some cases of M1, M5a, M7, and L2 are morphologically similar. In such cases, cytochemical stains can provide an inexpensive and available diagnostic tool. M1 is positive for SBB and MPO. M5a is usually NSE positive, whereas SBB and MPO are negative. M7 usually is ANA esterase, PAS, and AP reactive, and do not stain with SBB, MPO, and ANB esterases. The megakaryocytic lineage… CONTINUE READING

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