The use of comparative genomic hybridization to characterize genome dynamics and diversity among the serotypes of Shigella

@inproceedings{Peng2006TheUO,
  title={The use of comparative genomic hybridization to characterize genome dynamics and diversity among the serotypes of Shigella},
  author={Junping Peng and Xiaobing Zhang and Junxing Yang and Jing Wang and Eungi Yang and Wen Bin and Candong Wei and Meisheng Sun and Qi Jin},
  booktitle={BMC Genomics},
  year={2006}
}
Compelling evidence indicates that Shigella species, the etiologic agents of bacillary dysentery, as well as enteroinvasive Escherichia coli, are derived from multiple origins of Escherichia coli and form a single pathovar. To further understand the genome diversity and virulence evolution of Shigella, comparative genomic hybridization microarray analysis was employed to compare the gene content of E. coli K-12 with those of 43 Shigella strains from all lineages. For the 43 strains subjected to… CONTINUE READING
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