The use of cisplatinum for treatment of malignant glioma.

  title={The use of cisplatinum for treatment of malignant glioma.},
  author={G Witman and Ed C. Cadman and D T Kapp and Elmar Wagner},
  journal={Medical hypotheses},
  volume={8 4},
Standard chemotherapy for malignant gliomas has not generally been successful. Recent reports have suggested that cis-diammine-dichloroplatinum is preferentially accumulated into brain tumors compared to surrounding brain tissue. A patient who had failed radiation treatments and multiple other chemotherapeutic agents responded both clinically and radiographically to this new drug. This clinical observation, when combined with the tissue distribution of cis-diamminedichloroplatinum, would… CONTINUE READING