The use of chromosomal aberrations in human lymphocytes for biological dosimetry.

@article{Edwards1997TheUO,
  title={The use of chromosomal aberrations in human lymphocytes for biological dosimetry.},
  author={Alan A Edwards},
  journal={Radiation research},
  year={1997},
  volume={148 5 Suppl},
  pages={
          S39-44
        }
}
The scoring of chromosomal aberrations in human lymphocytes provides the most sensitive method known for biological dosimetry. By scoring dicentrics in the full genome of 500 cells, average whole-body doses of about 0.1 Gy of X or gamma rays may be detected and higher doses estimated. Acute doses above about 0.2 Gy can be estimated more accurately than similar chronic doses. For radiations of higher LET, for example those encountered in the space environment, the limits of detection in grays… CONTINUE READING
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