The use of cannabinoids as anticancer agents

  title={The use of cannabinoids as anticancer agents},
  author={Guillermo Vasquez de Velasco and Sonia Hern{\'a}ndez-Tiedra and David D{\'a}vila and M I Mart{\'i}nez Lorente},
  journal={Progress in Neuro-Psychopharmacology and Biological Psychiatry},
It is well-established that cannabinoids exert palliative effects on some cancer-associated symptoms. In addition evidences obtained during the last fifteen years support that these compounds can reduce tumor growth in animal models of cancer. Cannabinoids have been shown to activate an ER-stress related pathway that leads to the stimulation of autophagy-mediated cancer cell death. In addition, cannabinoids inhibit tumor angiogenesis and decrease cancer cell migration. The mechanisms of… CONTINUE READING
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