The use of anti-T-cell receptor-Vbeta antibodies for the estimation of treatment success and phenotypic characterization of clonal T-cell populations in cutaneous T-cell lymphomas.

@article{Schwab2002TheUO,
  title={The use of anti-T-cell receptor-Vbeta antibodies for the estimation of treatment success and phenotypic characterization of clonal T-cell populations in cutaneous T-cell lymphomas.},
  author={Cornelia M Schwab and Joerg Willers and Eva M. Niederer and Elisabeth Ludwig and Thomas M. K{\"u}ndig and Peter Grob and Guenter Burg and Reinhard Dummer},
  journal={British journal of haematology},
  year={2002},
  volume={118 4},
  pages={1019-26}
}
Sézary syndrome and Mycosis fungoides are the most common forms of cutaneous T-cell lymphomas. To assess the response to different therapies especially in Sézary syndrome, it is helpful to monitor the percentage of circulating tumour cells in the blood. The use of T-cell receptor (TCR)-Vbeta specific monoclonal antibodies provides a suitable tool for detecting Sézary cells. In this study, we analysed the levels of clonal CD4+Vbeta+ cells of seven patients with various treatment modalities using… CONTINUE READING

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