The use of an anti-beta 2-glycoprotein-I assay for discrimination between anticardiolipin antibodies associated with infection and increased risk of thrombosis.

@article{McNally1995TheUO,
  title={The use of an anti-beta 2-glycoprotein-I assay for discrimination between anticardiolipin antibodies associated with infection and increased risk of thrombosis.},
  author={Teresa McNally and Gordon Purdy and Ian Mackie and Samuel J. Machin and David Alan Isenberg},
  journal={British journal of haematology},
  year={1995},
  volume={91 2},
  pages={471-3}
}
Antiphospholipid antibodies (aPAs), occurring in association with infection, are not generally associated with an increased risk of thrombosis. Anticardiolipin antibodies (aCL) from patients with infection, unlike those from patients with SLE, do not have the beta 2GPI cofactor requirements. Antibodies to beta 2GPI (alpha beta 2GPI) are more closely associated with a previous history of thrombosis than aCL in patients with SLE. In the present study we have investigated the reactivity of the… CONTINUE READING

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