The use of a selected ion monitoring technique to study the disposition of bupivacaine in mother, fetus, and neonate following epidural anesthesia for cesarean section.

@article{Kuhnert1981TheUO,
  title={The use of a selected ion monitoring technique to study the disposition of bupivacaine in mother, fetus, and neonate following epidural anesthesia for cesarean section.},
  author={Paul M. Kuhnert and Betty R. Kuhnert and Judith M. Stitts and Thomas L. Gross},
  journal={Anesthesiology},
  year={1981},
  volume={55 6},
  pages={
          611-7
        }
}
It is well known that the concentration of bupivacaine in umbilical cord blood at birth is low compared with the concentration in maternal blood. It is not clear whether this low fetal/maternal ratio (F/M) is due to decreased placental transfer or increased uptake by fetal tissues. The purposes of this study were to develop an appropriate analytic method and to clarify this issue by studying the disposition of bupivacaine in mother, fetus and neonate following epidural anesthesia. The study… CONTINUE READING

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