The use of a registry database in clinical trial design: Assessing the influence of entry criteria on statistical power and number of eligible patients

@article{Peelen2007TheUO,
  title={The use of a registry database in clinical trial design: Assessing the influence of entry criteria on statistical power and number of eligible patients},
  author={Linda Peelen and Niels Peek and Evert de Jonge and Gert Jan Scheffer and Nicolette de Keizer},
  journal={International journal of medical informatics},
  year={2007},
  volume={76 2-3},
  pages={176-83}
}
Randomized clinical trials (RCTs) are prospective empirical studies used to investigate the effect of a particular medical intervention. The design of a clinical trial is a delicate decision process, as each of the decisions that are taken in this process influences the eventual result of the clinical trial. Despite the efforts that are put into trial… CONTINUE READING