The use of Zn-desferrioxamine for radioprotection in mice, tissue culture, and isolated DNA.

Abstract

Redox-active metals mediate oxidative injury and might also potentiate radiation damage. The iron chelator desferrioxamine (DFO), which diminishes oxidative damage in many chemical and biological systems as well as in human subjects, has a controversial role in radiobiology and reportedly acts both as a radiosensitizer and a radioprotector. The present… (More)

Topics

Cite this paper

@article{Samuni1999TheUO, title={The use of Zn-desferrioxamine for radioprotection in mice, tissue culture, and isolated DNA.}, author={Yuval Samuni and Denise Coffin and A M Deluca and William G Degraff and D J Venson and Indu S Ambudkar and Mordechai Mottie Chevion and J. B. Mitchell}, journal={Cancer research}, year={1999}, volume={59 2}, pages={405-9} }