The use of Omegaven in treating parenteral nutrition-associated liver disease
@article{Park2011TheUO, title={The use of Omegaven in treating parenteral nutrition-associated liver disease}, author={K T Park and Colleen Nespor and Jon F. Kerner}, journal={Journal of Perinatology}, year={2011}, volume={31}, pages={S57-S60} }
Parenteral nutrition (PN), containing fat emulsions derived from soybean, has been implicated in the progression of PN-associated liver disease and cholestasis, particularly in infants with short bowel syndrome. Clinical use of Omegaven, a parenteral fish-oil emulsion, has been shown in recent studies to be a promising therapy to reverse liver disease and cholestasis. This review summarizes the rationale, relevant clinical investigations and future direction of Omegaven therapy for PN-dependent… CONTINUE READING
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