The use of Matrigel at low concentration enhances in vitro blastocyst formation and hatching in a mouse embryo model.

@article{Lazzaroni1999TheUO,
  title={The use of Matrigel at low concentration enhances in vitro blastocyst formation and hatching in a mouse embryo model.},
  author={L Lazzaroni and Francesco Maria Fusi and Nicola Doldi and Augusto Ferrari},
  journal={Fertility and sterility},
  year={1999},
  volume={71 6},
  pages={1133-7}
}
OBJECTIVE To determine the effect of Matrigel at a low concentration on the growth of mouse embryos in culture. DESIGN Randomized case-control study of mouse embryos. SETTING An academic research environment. ANIMALS Mouse embryos. INTERVENTION(S) Embryos were cultured in Quinn's or Celbio's human tubal fluid (HTF) enriched with 1.5% bovine serum albumin and 0.8% liquid Matrigel. Each HTF was compared with the same medium devoid of Matrigel. Afterward, Quinn's and Celbio's HTF, both… CONTINUE READING