The use of MR imaging as an outcome measure in multiple sclerosis clinical trials.


MR imaging is an integral part of multiple sclerosis (MS) clinical trials. It provides the primary efficacy outcome of preliminary proof-of-concept studies and important corroborating data as secondary and exploratory outcomes in pivotal trials. At all stages of drug development, MR imaging provides important information on the kinetics and magnitude of… (More)
DOI: 10.1016/j.nic.2008.06.008