The use of 5-lipoxygenase inhibitors and leukotriene receptor antagonists in the treatment of chronic asthma.

@article{Sorkness1997TheUO,
  title={The use of 5-lipoxygenase inhibitors and leukotriene receptor antagonists in the treatment of chronic asthma.},
  author={Christine A. Sorkness},
  journal={Pharmacotherapy},
  year={1997},
  volume={17 1 Pt 2},
  pages={50S-54S}
}
With the elucidation of asthma as a chronic inflammatory disease, therapeutic approaches have shifted from treatment of symptoms with bronchodilators to treatment of the underlying disease with antiinflammatory agents. Along with concerns about corticosteroid side effects on the part of both physicians and patients, this shift has motivated researchers to develop and test new agents with antiinflammatory capabilities. The leukotrienes are endogenous mediators with three inflammatory effects… CONTINUE READING

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