The urokinase receptor is a major vitronectin-binding protein on endothelial cells.

@article{Kanse1996TheUR,
  title={The urokinase receptor is a major vitronectin-binding protein on endothelial cells.},
  author={Sandip M Kanse and Curt Kost and Olaf G. Wilhelm and Peter Andr{\'e} Andreasen and Klaus Theo Preissner},
  journal={Experimental cell research},
  year={1996},
  volume={224 2},
  pages={344-53}
}
We have previously demonstrated that vitronectin (VN), a morphoregulatory protein in the vessel wall, is internalized and translocated to the subendothelial matrix by an integrin-independent mechanism (J. Histochem. Cytochem. 41, 1823-1832, 1993). The cell surface component which mediates the initial contact of VN with endothelial cells is defined here. The specific binding of VN to endothelial cells demonstrated the following properties: a threefold increase after phorbol ester treatment; 85… CONTINUE READING

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