The uptake of protons by heme-linked ionizable groups on azide binding to methemoglobin.

@article{Okonjo1987TheUO,
  title={The uptake of protons by heme-linked ionizable groups on azide binding to methemoglobin.},
  author={Kehinde Onwochei Okonjo and Fernando J. Vega-Catalan},
  journal={European journal of biochemistry},
  year={1987},
  volume={169 2},
  pages={413-6}
}
When azide ion reacts with methemoglobin in unbuffered solution the pH of the solution increases. This phenomenon is associated with increases in the pK values of heme-linked ionizable groups on the protein which give rise to an uptake of protons from solution. We have determined as a functional of pH the proton uptake, delta h+, on azide binding to… CONTINUE READING