The upregulation of metallothionein-1 expression in areca quid chewing-associated oral squamous cell carcinomas.

@article{Lee2008TheUO,
  title={The upregulation of metallothionein-1 expression in areca quid chewing-associated oral squamous cell carcinomas.},
  author={Shiuan-Shinn Lee and Shun-Fa Yang and Yung-chuan Ho and cHung-Hung tSai and Yu-Chao Chang},
  journal={Oral oncology},
  year={2008},
  volume={44 2},
  pages={
          180-6
        }
}
Metallothioneins (MTs) are a family of low molecular weight, cysteine-rich, inducible, intracellular proteins that bind heavy metals with high affinity. MT-1 is known as a stress-inducible protein and functions as an antioxidant enzyme. Areca quid chewing is a major risk factor in the development and further progression of oral squamous cell carcinoma (OSCC). The aim of this study was to compare MT-1 expression in normal human oral epithelium and OSCC and further explore the potential mechanism… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 19 CITATIONS

Similar Papers

Loading similar papers…