The unknotted strands of life: knots are very rare in RNA structures

@inproceedings{Micheletti2014TheUS,
  title={The unknotted strands of life: knots are very rare in RNA structures},
  author={Cristian Micheletti and Marco Di Stefano and Henri Orland},
  year={2014}
}
The ongoing effort to detect and characterize physical entanglement in biopolymers has so far established that knots are present in many globular proteins and also abound in viral DNA packaged inside bacteriophages. RNA molecules, on the other hand, have not yet been systematically screened for the occurrence of physical knots. We have accordingly… CONTINUE READING