The unique luminal staining pattern of cytokeratin 5/6 in adenoid cystic carcinoma of the breast may aid in differentiating it from its mimickers

@article{Nakai2016TheUL,
  title={The unique luminal staining pattern of cytokeratin 5/6 in adenoid cystic carcinoma of the breast may aid in differentiating it from its mimickers},
  author={Tokiko Nakai and Shu Ichihara and Akiko Kada and Noriko Ito and Suzuko Moritani and Tomonori Kawasaki and Tomoko Uchiyama and Hiroe Itami and Kouhei Morita and Masato Takano and Maiko Takeda and Kinta Hatakeyama and Chiho Ohbayashi},
  journal={Virchows Archiv},
  year={2016},
  volume={469},
  pages={213-222}
}
Adenoid cystic carcinoma (AdCC) of the breast is an uncommon but distinct neoplasm composed of a dual cell population polarized around true glandular (luminal) spaces and pseudolumina. The aim of this study was to clarify whether various immunohistochemical markers (CK7, EMA, CD117, p63, calponin, CD10, S100, CK5/6, CK14, vimentin, and type IV collagen) can distinguish between the two cell types in classical AdCC (n = 14) and in collagenous spherulosis (n = 5). The sensitivity and specificity… CONTINUE READING
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