The unique electrical properties in an extracellular fluid of the mammalian cochlea; their functional roles, homeostatic processes, and pathological significance

@inproceedings{Nin2016TheUE,
  title={The unique electrical properties in an extracellular fluid of the mammalian cochlea; their functional roles, homeostatic processes, and pathological significance},
  author={F. Nin and Takamasa Yoshida and Seishiro Sawamura and Genki Ogata and Takeru Ota and Taiga Higuchi and Shingo Murakami and Katsumi Doi and Yoshihisa Kurachi and Hiroshi Hibino},
  booktitle={Pfl{\"u}gers Archiv - European Journal of Physiology},
  year={2016}
}
The cochlea of the mammalian inner ear contains an endolymph that exhibits an endocochlear potential (EP) of +80 mV with a [K+] of 150 mM. This unusual extracellular solution is maintained by the cochlear lateral wall, a double-layered epithelial-like tissue. Acoustic stimuli allow endolymphatic K+ to enter sensory hair cells and excite them. The positive EP accelerates this K+ influx, thereby sensitizing hearing. K+ exits from hair cells and circulates back to the lateral wall, which… CONTINUE READING
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