The underlying cellular mechanism of fibrosis.

  title={The underlying cellular mechanism of fibrosis.},
  author={Hans Peter Rodemann and Anke B. Binder and Angelika Burger and Nurtaç G{\"u}ven and Heidi Loeffler and Michael Bamberg},
  journal={Kidney international. Supplement},
Fibrosis is a common sequela of various exogenous insults to a variety of parenchymal tissues. The underlying mechanisms of the induction and progression of fibrosis both at the molecular and cellular level have not been clarified so far. In the present study the cellular processes that ultimately may lead to interstitial fibrosis are described using the model of radiation-induced terminal differentiation in the fibroblast/fibrocyte cell system. The data reported herein will provide evidence… CONTINUE READING

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