The underappreciated role of muscle in health and disease.

@article{Wolfe2006TheUR,
  title={The underappreciated role of muscle in health and disease.},
  author={Robert R. Wolfe},
  journal={The American journal of clinical nutrition},
  year={2006},
  volume={84 3},
  pages={
          475-82
        }
}
  • R. Wolfe
  • Published 2006
  • Biology, Medicine
  • The American journal of clinical nutrition
Muscle plays a central role in whole-body protein metabolism by serving as the principal reservoir for amino acids to maintain protein synthesis in vital tissues and organs in the absence of amino acid absorption from the gut and by providing hepatic gluconeogenic precursors. Furthermore, altered muscle metabolism plays a key role in the genesis, and therefore the prevention, of many common pathologic conditions and chronic diseases. Nonetheless, the maintenance of adequate muscle mass… Expand
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