The uncertainty principle and industry-sponsored research.

@article{Djulbegovic2000TheUP,
  title={The uncertainty principle and industry-sponsored research.},
  author={Benjamin Djulbegovic and Mensura Lacevic and Alan M Cantor and Karen K. Fields and Charles L Bennett and Jared R. Adams and Nicole M. Kuderer and Gary H. Lyman},
  journal={Lancet},
  year={2000},
  volume={356 9230},
  pages={635-8}
}
BACKGROUND Reporting of pharmaceutical-industry-sponsored randomised clinical trials often result in biased findings, either due to selective reporting of studies with non-equivalent arms or publication of low-quality papers, wherein unfavourable results are incompletely described. A randomised trial should be conducted only if there is substantial uncertainty about the relative value of one treatment versus another. Studies in which intervention and control are thought to be non-equivalent… CONTINUE READING
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