The ulcer sleuths: The search for the cause of peptic ulcers

@article{Yeomans2011TheUS,
  title={The ulcer sleuths: The search for the cause of peptic ulcers},
  author={Neville D Yeomans},
  journal={Journal of Gastroenterology and Hepatology},
  year={2011},
  volume={26}
}
  • N. Yeomans
  • Published 1 January 2011
  • Medicine
  • Journal of Gastroenterology and Hepatology
The search for the cause or causes of peptic ulcers has been a long one. It was recognised as early as the 19th Century that damage to the stomach or duodenal bulb was likely to result if the resistance of their mucosae to luminal acid was for some reason impaired. An early theory suggested microscopic vascular occlusion leading to local infarction could be the initiating event but evidence was lacking. Excessive acid secretion is seen in some patients but not in many so is implausible as the… 

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