The ubiquitin code of yeast permease trafficking.

  title={The ubiquitin code of yeast permease trafficking.},
  author={Elsa Lauwers and Zoi Erpapazoglou and Rosine Haguenauer-Tsapis and Bruno Andr{\'e}},
  journal={Trends in cell biology},
  volume={20 4},
Yeast permeases, that act as transporters for nutrients including amino acids, nucleobases and metals, provide a powerful model system for dissecting the physiological control of membrane protein trafficking. Modification of these transporters by ubiquitin is known to target them for degradation in the vacuole, the degradation organelle of fungi. Recent studies have uncovered the role of specific adaptors for recruiting the Rsp5 ubiquitin ligase to these proteins. In addition, the role of… CONTINUE READING
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