The type VI secretion system sheath assembles at the end distal from the membrane anchor

Abstract

The bacterial Type VI secretion system (T6SS) delivers proteins into target cells using fast contraction of a long sheath anchored to the cell envelope and wrapped around an inner Hcp tube associated with the secreted proteins. Mechanisms of sheath assembly and length regulation are unclear. Here we study these processes using spheroplasts formed from… (More)
DOI: 10.1038/ncomms16088

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