The type III secretion system of Vibrio alginolyticus induces rapid apoptosis, cell rounding and osmotic lysis of fish cells.

@article{Zhao2010TheTI,
  title={The type III secretion system of Vibrio alginolyticus induces rapid apoptosis, cell rounding and osmotic lysis of fish cells.},
  author={Zhe Zhao and Chang Chen and Chao-Qun Hu and Chun-hua Ren and Jing-Jing Zhao and Lv-ping Zhang and Xiao Hai Jiang and Peng Luo and Qing-Bai Wang},
  journal={Microbiology},
  year={2010},
  volume={156 Pt 9},
  pages={
          2864-72
        }
}
Vibrio alginolyticus is a Gram-negative bacterium and has been recognized as an opportunistic pathogen in humans as well as marine animals. However, the virulence mechanisms for this species of Vibrio have not been elucidated. This study characterized multiple mechanisms that induce cell death in fish cells upon infection with a V. alginolyticus strain, ZJO. The bacterium required its type III secretion system (T3SS) to cause rapid death of infected fish cells. Dying cells exhibited some… CONTINUE READING

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ExsE Is a Negative Regulator for T3SS Gene Expression in Vibrio alginolyticus

Jinxin Liu, Shao-Yeh Lu, +5 authors Zhe Zhao
  • Front. Cell. Infect. Microbiol.
  • 2016
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