The type I macrophage scavenger receptor binds to gram-positive bacteria and recognizes lipoteichoic acid.

@article{Dunne1994TheTI,
  title={The type I macrophage scavenger receptor binds to gram-positive bacteria and recognizes lipoteichoic acid.},
  author={David W. Dunne and David Resnick and Jacquie L Greenberg and Monty Krieger and Keith A. Joiner},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1994},
  volume={91 5},
  pages={
          1863-7
        }
}
Macrophage scavenger receptors exhibit unusually broad binding specificity for polyanionic ligands and have been implicated in atherosclerosis and various host defense functions. Using a radiolabeled, secreted form of the type I bovine macrophage scavenger receptor in an in vitro binding assay, we have found that this receptor binds to intact Gram-positive bacteria, including Streptococcus pyogenes, Streptococcus agalactiae, Staphylococcus aureus, Enterococcus hirae, and Listeria monocytogenes… CONTINUE READING
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