The type 2 deiodinase (DIO2) A/G polymorphism is not associated with glycemic traits: the Framingham Heart Study.

@article{Maia2007TheT2,
  title={The type 2 deiodinase (DIO2) A/G polymorphism is not associated with glycemic traits: the Framingham Heart Study.},
  author={Ana L. L. M. Maia and Jos{\'e}e Dupuis and Alisa Knodle Manning and Chunyu Liu and James B. Meigs and L. Adrienne Cupples and P. R. Larsen and Caroline Fox},
  journal={Thyroid : official journal of the American Thyroid Association},
  year={2007},
  volume={17 3},
  pages={199-202}
}
BACKGROUND Type 2 deiodinase plays a critical role in thyroid hormone homeostasis. A single nucleotide polymorphism in DIO2 gene (A/G) in humans has been associated with a approximately 20% lower glucose disposal rate and greater insulin resistance in type 2 diabetes (DM2) patients. OBJECTIVE This study was designed to test whether homozygosity for the… CONTINUE READING