The two gene pairs encoding H2A and H2B play different roles in the Saccharomyces cerevisiae life cycle.

@article{Norris1987TheTG,
  title={The two gene pairs encoding H2A and H2B play different roles in the Saccharomyces cerevisiae life cycle.},
  author={David Norris and Mary Ann Osley},
  journal={Molecular and cellular biology},
  year={1987},
  volume={7 10},
  pages={3473-81}
}
We have isolated Saccharomyces cerevisiae mutants bearing deletions of one or the other of the two divergently transcribed gene pairs encoding H2A and H2B. The deletions produced diverse effects on the yeast life cycle. Deletion of TRT1, one of the H2A-H2B gene pair sets, affected mitotic growth, sporulation, spore germination, the heat shock response, and exit from the stationary phase; deletion of TRT2, the other H2A-H2B gene pair set, had negligible effects on these same processes. Using a… CONTINUE READING

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