The tunica albuginea of the human testis is characterized by complex contraction and relaxation activities regulated by cyclic GMP.

@article{Middendorff2002TheTA,
  title={The tunica albuginea of the human testis is characterized by complex contraction and relaxation activities regulated by cyclic GMP.},
  author={Ralf Middendorff and Dieter M{\"u}ller and Marco Mewe and Amal K. Mukhopadhyay and Adolf F. Holstein and Michail S. Davidoff},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2002},
  volume={87 7},
  pages={3486-99}
}
The mechanisms responsible for the initial transport of immotile sperm from the testis into the epididymis are still poorly understood. We show here by electron microscopy and immunohistochemical approaches that the tunica albuginea of the human testis contains abundantly contractile elements. This tissue is also distinguished by extraordinarily high concentrations of cyclic GMP (cGMP)-dependent protein kinase I, known to mediate cGMP-dependent relaxation. Atrial natriuretic peptide (ANP) and… CONTINUE READING

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