The tumor suppressor protein TSLC1 is involved in cell-cell adhesion.

  title={The tumor suppressor protein TSLC1 is involved in cell-cell adhesion.},
  author={Mari Masuda and Mika Yageta and Hiroshi Fukuhara and Masami Kuramochi and Tomoko Maruyama and A. Nomoto and Yoshinori Murakami},
  journal={The Journal of biological chemistry},
  volume={277 34},
TSLC1 is a tumor suppressor gene encoding a member of the immunoglobulin (Ig) superfamily. The significant homology of its extracellular domain with those of other Ig superfamily cell adhesion molecules (IgCAMs) has raised the possibility that TSLC1 participates in cell-cell interactions. In this study, the physiological properties of TSLC1 were investigated in Madin-Darby canine kidney (MDCK) cells expressing TSLC1 tagged with green fluorescent protein (GFP) as well as in the cells that… CONTINUE READING


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Physiological Characterization of the Tumor Suppressor Protein TSLC1

  • P. Guilford
  • J. Biol. Chem. 10.1074/jbc.M203620200
  • 1999

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