The tumor microenvironment of colorectal cancer: stromal TLR-4 expression as a potential prognostic marker

@inproceedings{Cammarota2010TheTM,
  title={The tumor microenvironment of colorectal cancer: stromal TLR-4 expression as a potential prognostic marker},
  author={Rosaria Cammarota and Valentina Bertolini and Giuseppina Pennesi and Eraldo O. Bucci and Ornella Gottardi and Cecilia Garlanda and Luigi Laghi and Massimo Costanzo Barberis and Fausto Sessa and Douglas M Noonan and Adriana Albini},
  booktitle={Journal of Translational Medicine},
  year={2010}
}
Colorectal cancer can be efficiently treated when found at early stages, thus the search for novel markers is of paramount importance. Since inflammation is associated with cancer progression and angiogenesis, we investigated expression of cytokines like IL-6 and other mediators that play a key role in the innate immune system, in particular toll like receptor 4 (TLR4), in the microenvironment of lesions from different stages of colon disease progression, from ulcerative colitis to adenoma and… CONTINUE READING

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Nonsteroidal anti-inflammatory Cammarota et al

  • MV Grau, RS Sandler, +7 authors JA Baron
  • Journal of Translational Medicine
  • 2010
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