The tumor-associated antigen 90K/Mac-2-binding protein secreted by human colon carcinoma cells enhances extracellular levels of promatrilysin and is a novel substrate of matrix metalloproteinases-2, -7 (matrilysin) and -9: Implications of proteolytic cleavage.

@article{Ulmer2010TheTA,
  title={The tumor-associated antigen 90K/Mac-2-binding protein secreted by human colon carcinoma cells enhances extracellular levels of promatrilysin and is a novel substrate of matrix metalloproteinases-2, -7 (matrilysin) and -9: Implications of proteolytic cleavage.},
  author={Tricia A Ulmer and Vicki Keeler and Sabine Andr{\'e} and Hans-Joachim Gabius and Lambert C. Loh and Suzanne Lafert{\'e}},
  journal={Biochimica et biophysica acta},
  year={2010},
  volume={1800 3},
  pages={336-43}
}
BACKGROUND The tumor-associated antigen 90K (TAA90K)/Mac-2-binding protein is expressed at elevated level in cancerous tissues and associated with poor prognosis. Since TAA90K has been implicated in the restructuring of the extracellular matrix, we examined the functional relationship between colon cancer cell-derived TAA90K and the matrix metalloproteinase… CONTINUE READING