The tumor antigens and the early functions of polyoma virus

  title={The tumor antigens and the early functions of polyoma virus},
  author={Hans T{\"u}rler},
  journal={Molecular and Cellular Biochemistry},
Polyoma virus (Py) tumor (T) antigens are the proteins specified by the early region of the viral genome. They are responsible for most biological effects caused by this oncogenic virus, i.e. induction of tumors, cell transformation and most of the virus-induced events observed in productive and transforming infection. By immunoprecipitation with antitumor serum followed by gel electrophoresis three major Py T-antigens have been characterized: large Tantigen (IT) with an apparent MT of about… CONTINUE READING
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