The trypanolytic factor of human serum

  title={The trypanolytic factor of human serum},
  author={E. Pays and Benoit Vanhollebeke and Luc Vanhamme and Françoise Paturiaux-Hanocq and Derek P. Nolan and David P{\'e}rez-Morga},
  journal={Nature Reviews Microbiology},
African trypanosomes (the prototype of which is Trypanosoma brucei brucei) are protozoan parasites that infect a wide range of mammals. Human blood, unlike the blood of other mammals, has efficient trypanolytic activity, and this needs to be counteracted by these parasites. Resistance to this activity has arisen in two subspecies of Trypanosoma brucei — Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense — allowing these parasites to infect humans, and this results in sleeping… CONTINUE READING


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